This case study explores how leading diagnostic labs, research centers, and pharmaceutical companies are leveraging the Pannoramic 250 Flash III DX, Pannoramic 150 DX, Pannoramic 75 DX, and Pannoramic Flash MIDI DX scanners to overcome industry challenges, accelerate digital pathology workflows, and enhance diagnostic accuracy.
Key Challenges in Diagnostic Toxicological Pathology & Neuropathology
Demand for High-Resolution Imaging
• Toxicological and neuropathological studies require the detection of minuscule
morphological changes at a cellular level.
• Traditional microscopy can limit visibility and analysis of fine details, impacting
diagnostic accuracy.
High Sample Throughput & Workflow Bottlenecks
• Large-scale studies demand rapid, automated processing of hundreds of tissue samples
per day.
• Manual slide evaluation can slow down workflows and increase human error
Regulatory Compliance & Data Standardization
• Digital pathology in toxicological and neuropathology research requires DICOMcompatible imaging and secure LIS/HIS integration.
• Ensuring regulatory adherence (e.g., IVDR compliance) is critical for clinical validation.
Remote Collaboration & Multisite Review
• Toxicologic and neuropathology studies often involve multi-institutional collaborations.
• Efficient telepathology solutions are essential for remote consultation, second opinions,
and expert collaboration.
Optimizing Diagnostic Toxicologic Pathology & Neuropathology
Complete Whole Slide Imaging Solutions with Pannoramic DX Digital Scanners
Each Pannoramic DX scanner provides automated, high-resolution whole slide imaging with AI-driven image analysis, ensuring rapid, reproducible, and high-accuracy diagnostics.
№1. Best for large-scale toxicologial and neuropathology labs requiring ultra-high-throughput scanning
Key Benefits
- High-Speed, High-Capacity Pathology Imaging.
- High-capacity scanning (up to 300 slides per batch) with AI-driven automation.
- Ultra-resolution brightfield scanning enables detailed neuropathological analysis, capturing fine morphological changes in brain and nerve tissue.
- AI-powered tissue detection reduces scanning errors, ensuring reliable toxicological pathology assessments.
- DICOM format compatibility for secure data integration within pathology workflows.
Pannoramic 250 Flash III DX Digital Scanner
№2. Best for high-throughput toxicological pathology with advanced imaging requirements.
Key Benefits
- Precision & Performance in a Compact Design
- High-resolution (0.1 um/pixel) brightfield imaging at 100x magnification captures microscopic cellular alterations.
- Supports automated tissue detection, Z-stack, and extended focus imaging for complex neuropathology assessments.
- AI-driven cover glass detection optimizes scanning quality and eliminates artifacts.
Pannoramic 150 DX Digital Scanner
№3. Best for mid-sized toxicological labs and neuropathology departments needing a balance of capacity and compact design.
Key Benefits
- High-throughput, space-saving efficiency.
- Up to 75-slide automated scanning with ultra-resolution imaging.
- Compact footprint ideal for space-constrained diagnostic settings.
- Multilayer (Z-stack) scanning and AI-enhanced image analysis for deep tissue visualization in neuropathology.
- Seamless integration with laboratory information systems for optimized workflows.
Pannoramic 75 DX Digital Scanner
№4. Best for small-scale toxicological pathology labs requiring rapid, high-resolution diagnostics.
Key Benefits
- Specialized high-speed imaging.
- Flash illumination technology provides high-speed, high-contrast imaging of toxicology and neuropathology slides.
- Achieves up to 0.12 um/pixel resolution for fine cellular visualization.
- 12-slide batch processing with minimal footprint optimizes space and workflow efficiency.
- Ideal for specialized neuropathology studies, including brain tumors, degenerative diseases, and toxicologic neuropharmacology research.
Pannoramic Flash MIDI DX Digital Scanner
Large Volume Scanners for Toxicologic Pathology & Neuropathology
For large-scale diagnostic toxicologic pathology and neuropathology applications, selecting the right high-capacity whole slide imaging scanner is critical for maximizing efficiency, precision, and workflow integration. 3DHISTECH’s high-throughput Pannoramic DX scanners provide automated, AI-driven scanning with exceptional imaging accuracy, ensuring reliable and scalable solutions for large diagnostic institutions, pharmaceutical institutions, and regulatory pathology institutes.
Each of the following scanners is engineered for uninterrupted high-throughput imaging, optimized for large diagnostic facilities, regulatory toxicology labs, and neuropathology research centers.
№1. Best for toxicologic pathology institutions, neuropathology research centers, and regulatory labs requiring maximum capacity and automation
This scanner is a gold standard for large-scale pathology – it enables pharmaceutical companies, regulatory agencies, and large hospitals to handle complex toxicology and neuropathology case reviews at an unprecedented scale.
Key Benefits
- Unmatched throughput for large-scale Labs
- Supports up to 1200 slides per batch – ideal for high-volume toxicological pathology studies.
- Ultra-resolution imaging at 40x, 80x, and 100x magnification for detecting fine neuropathological changes.
- Automated Z-stack scanning captures multi-layer tissue structures essential for neuropathology and toxicology.
- Safety container system isolates damaged or misaligned slides, preventing workflow disruptions.
- AI-driven tissue recognition enhances diagnostic accuracy and standardization.
Pannoramic 1000 DX Digital Scanner
№2. Best for: neuropathology labs and toxicologic pathology departments requiring polarization imaging and cytopathology analysis
This scanner is ideal for neuropathology applications requiring polarization imaging (e.g., detecting birefringent amyloid plaques in Alzheimer’s) and high-throughput toxicologic assessments.
Key Benefits
- High-speed, polarization-enabled imaging
- Scans up to 480 slides per batch for high-throughput toxicology and pathology workflows.
- Advanced polarization imaging detects birefringent structures, such as amyloid plaques in neurodegenerative diseases.
- Brightfield & Z-stack imaging for multilayer cytopathology scanning, optimizing tissue depth analysis.
- Anti-vibration base for stable, high-resolution imaging – essential for precise neuropathology studies.
- Safety container system prevents workflow interruptions by handling problematic slides separately.
Pannoramic 480 DX Digital Scanner
№3. Best for mid-to-large toxicological pathology labs needing rapid scanning of diverse slide types
This scanner is versatile and cost-effective, making it ideal for toxicologic pathology labs that handle diverse tissue types.
Key Benefits
- Precision & speed for high-throughput toxicology & neuropathology
- 300-slide batch capacity ensures efficient high-throughput toxicological and neuropathology studies.
- AI-powered tissue detection automates slide scanning, enhancing accuracy and workflow efficiency.
- Brightfield imaging with ultra-high resolution supports detailed cellular assessments.
- Automated scanning for histology, peripheral blood smears, and cytopathology.
- Optional fluorescence upgrade for additional research applications.
Pannoramic 250 Flash III DX Digital Scanner
Key Benefits for Toxicological Pathology & Neuropathology Labs
Faster, More Reliable Diagnostics
Automated scanning and AI-assisted image analysis reduce diagnostic turnaround time, increasing efficiency.
High-Resolution Imaging for Critical Assessments
Ultra-high-resolution scanning (down to 0.1 um/pixel) captures fine morphological changes essential for toxicologic and neuropathological studies.
AI-Driven Automation for Enhanced Accuracy
Automated tissue and coverslip detection, coupled with Z-stack scanning, ensures precision imaging for neuropathology and toxicology applications.
Seamless Digital Workflow & Remote Collaboration
Full DICOM compatibility, LIS/HIS integration, and telepathology solutions facilitate collaborative diagnostics across institutions.
Cost-Effective, Scalable Solutions
Whether for large research institutions or small pathology labs, the Pannoramic DX scanners provide scalable, cost-effective digital pathology solutions.
A Digital Pathology Transformation for Toxicological & Neuropathology Diagnostics
By integrating 3DHISTECH’s Pannoramic DX Whole Slide Imaging Solutions, leading toxicological pathology and neuropathology labs have significantly improved diagnostic accuracy, workflow efficiency, and collaborative research capabilities. With AI-powered automation, ultra-resolution imaging, and seamless LIS/HIS integration, these scanners eliminate workflow bottlenecks and optimize pathology diagnostics, ensuring faster, more accurate toxicological and neuropathological assessments.