The TMA molmed: Automated High-Speed Solution for Tissue Microarray Creation and Molecular Sampling.
A fully automated, high-speed solution for molecular sampling and tissue microarray creation from FFPE blocks. A 2-in-1 breakthrough with its dual functionality: precision tissue microarrayer and an advanced laser microdissection-like tissue sampler. taking 0.2 mm diameter x 0.3-0.5 mm deep sample cores.
TMA molmed prepares TMA blocks from biological specimens and samples of human or animal tissues. Typical applications include, but are not limited to the following:
- Laboratories at hospitals and clinics
- Pathology departments at hospitals and clinics
- Biobanks
- Research centers, in particular cancer research centers
- Pharmaceutical companies
- Toxicopathology laboratories
Key Features
Fully automated control
The TMA molmed is the fastest, fully automated tissue microarrayer capable of molecular analysis: PCR, dPCR sequencing, etc. on the market.
Capacity:
- 9 modular donor or recepient blocks
- 2 macro donor or recepient blocks (megablock)
Maximum Cores per TMA Block
- 0.6 mm (maximum number of cores/TMA block is 558)
- 1 mm (maximum number of cores/TMA block is 286)
- 1.5 mm (maximum number of cores/TMA block is 135)
- 2 mm (maximum number of cores/TMA block is 84)
- 3mm (maximum number of cores/TMA block is 40)
Fast operation
- 200-250 cores transfered/hour
- Simultaneous loading, imaging, drilling and punching
Smart automation
- Automatic block height measurement to ensure the embedded cores are in alignment with the recipient block surface
- Fully automated barcode reading
- Automatic donor block and label image saving for reference
- Automatic project data saving into database
PCR extraction function
- 6 PCR cassettes
- 10 PCR tubes / cassette
- Use of cleaning block to avoid cross contamination
- Extracted FFPE tissue samples are ready for DNA extraction and PCR analysis with commercially available kits
Other features
- Custom recipient block design and production
- Ability to create up to 12 identical TMA blocks
- Digital slide overlay for more precise tissue core (sample) selection
- Ability to import clinical data
- TMA data export in various file formats (ods, xls, xlsx, csv, xml)
Specifications
| Capacity, Blocks | 9 (Donor or Recepient), 2 (Macro Donor or Recepient |
| Core diameter, mm | 0.2 (surface), 0.6, 1, 1.5, 2, 3 |
| Maximum number of cores/TMA block | 558 (0.6 mm), 286 (1 mm), 135 (1.5 mm), 84 (2 mm), 40 (3 mm) |
| Speed, core/hour | 200-250 |
| Donor block image recording | Yes |
| Use of MRXS digital slide and/or JPEG digital image for sample designation | Yes |
| Barcode reading | 1D and 2D |
| Data export | ods, xls, xlsx, csv, xml |
| Dimensions, cm (W x D x H) | 50 x 50 x 42 |
| Weight (kg) | 30 |
Software
TMA molmed is controlled by the latest version of the TMA Control software. This software is the best solution for TMA block design and creation. It has advanced features for layout design and tissue core selection. A fully automated tool for overlapping an annotated digital slide with the donor block image helps precise core selection. During the TMA project the software automatically saves all the TMA data, which will be an invaluable source of information during TMA slide analysis by TMA Module software.
