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Pannoramic MIDI III Digital Scanner

The Pannoramic MIDI III is a versatile high-performance digital slide scanner designed for advanced pathology research. With 12-slide capacity, high-speed brightfield and fluorescent scanning, and exceptional resolution down to 0.10 um/pixel, it offers unmatched precision. Its compact design and automated workflows make it ideal for research applications, including biomarker analysis, multiplex imaging, and tissue morphology studies.
PANNORAMIC™ MIDI III

Scan Examples

Pannoramic MIDI III Digital Scanner

High Performance Brightfield and Fluorescent Scanning for Advanced Pathology Research

The Pannoramic MIDI III Digital Scanner is a compact, high-performance whole-slide imaging solution tailored for advanced pathology research, which encompasses the in-depth study of tissue morphology, molecular biomarkers, and disease processes at a cellular level. Researchers in this field rely on high-resolution imaging to explore complex tissue structures, analyze biomarker expressions, and advance discoveries in areas such as cancer biology, neuroscience, immunology, and drug development. With a focus on precision and adaptability, the Pannoramic MIDI III seamlessly integrates brightfield and fluorescent scanning capabilities with a 12-slide capacity, delivering exceptional efficiency for high-throughput imaging workflows. Its leading optical system achieves outstanding resolution down to 0.10 µm/pixel, providing ultra-sharp clarity and enabling the visualization of even the finest tissue details for accurate, reliable results.

What sets the Pannoramic MIDI III apart is its dual-camera system with a motorized camera changer, seamlessly switching between brightfield and fluorescence modes. The inclusion of a high-end fluorescent light engine with 9 filter positions and support for up to 45 fluorescent channels makes it ideal for multiplex biomarker analysis and fluorescence studies.

Its automated tissue detection, barcode reading, and optional Z-stack and Extended Focus scanning provide unparalleled functionality, saving time and minimizing manual intervention. Compact yet robust, the Pannoramic MIDI III stands out with its user-friendly design and low maintenance requirements, offering research laboratories a powerful, reliable, and cost-effective solution that outperforms conventional scanners in precision, flexibility, and ease of use.

Key Features:

Dual-Mode Scanning: Brightfield and Fluorescence

Seamlessly switch between high-speed brightfield imaging and advanced fluorescent scanning, offering unparalleled flexibility for a wide range of research applications.

Achieves ultra-sharp clarity with resolutions down to 0.10 µm/pixel, ensuring precise visualization of even the smallest tissue details for confident analysis.

Fully automated loading, scanning, and barcode reading of up to 12 slides, maximizing efficiency and throughput for high-volume research workflows.

Equipped with a 9-position filter system and support for up to 45 fluorescent channels, ideal for multiplex biomarker analysis and advanced molecular research.

A space-saving, robust system with minimal maintenance requirements, delivering reliability without compromising performance.

Optional Z-stack (multilayer) scanning and Extended Focus capabilities allow for detailed 3D tissue analysis and sharp, fully focused images, catering to specialized research needs.

Capacity

12 slides (automatic loading and scanning)

Scanning

Dual-mode scanning (brightfield and fluorescence) with area scanning and autofocus

Brightfield Scanning Speed

1 minute 30 seconds for a 15 mm x 15 mm area at 0.19 µm/pixel resolution

Fluorescence Scanning Speed

8 minutes 30 seconds for a 15 mm x 15 mm area with 3 fluorescent channels at 20 ms exposure time

Throughput

Optimized for high-throughput workflows with fast automated scanning and slide handling

Objectives

Plan-Apochromat 4x/0.16 NA, 20x/0.8 NA, and 40x Corr/0.95 NA objectives

Number of Supported Objectives

3 (motorized objective changer)

Brightfield Magnification

Up to 103x

Fluorescence Magnification

Up to 98x

Image Output

MRXS format with export options to JPG, JPEGXR, BMP, PNG, TIFF, Roche TIFF, SVS, and DICOM

Slide Compatibility

Slides measuring 75.0–76.2 mm (L) x 25.0–26.0 mm (W) x 0.9–1.2 mm (T) with No. 1 or 1.5 coverslips (0.13–0.19 mm)

Flash scanning

Not explicitly specified

Brightfield Scanning (resolution)

Down to 0.10 µm/pixel (with 40x objective)

Fluorescence scanning (resolution)

Down to 0.10 µm/pixel (with 40x objective and 1.6x adapter)

Brightfield Illumination

LED-based transmitted light with 3DHISTECH LED FLASH technology (average lifetime ~60,000 hours)

Fluorescence Illumination

Fluorescence Light Engine with 8 solid-state sources (LEDs and lasers, 380–740 nm)

Tissue Detection

Automatic threshold tissue detection with USB preview camera

Slide Size

75.0–76.2 mm (L) x 25.0–26.0 mm (W) x 0.9–1.2 mm (T)

Focus Layering

Optional Z-stack (multilayer) scanning with 1–30 layers and adjustable distances (0.2–2 µm)

Barcode Reading

Supports 1D and 2D barcode types, including Code39, Code128, QR, and Data Matrix

Dimensions

Approx. 840 mm x 635 mm x 550 mm (scanner unit)

Weight

Approx. 43.5 kg (scanner unit)

Pannoramic MIDI III Digital Scanner

Specifications

Customizable Configurations

Additional Options:

  • Multilayer (Z-Stack) Scanning
  • Extended Focus Scanning

Use Cases of Pannoramic MIDI III Digital Scanner

Explore the Use Cases

Biomedical research is experiencing a major shift with the integration of Digital Pathology and Micro-CT solutions, significantly improving tissue analysis, biomarker discovery, and disease modeling. Traditional microscopy methods have inherent limitations, such…
Botany and plant sciences rely on high-resolution imaging and precise analysis of plant tissues to understand disease mechanisms, stress responses, genetic modifications, and ecological changes. Traditional microscopy techniques limit research efficiency due…
Cancer research demands cutting-edge imaging technologies to enhance biomarker discovery, tumor profiling, and immuno-oncology advancements. Traditional histopathology techniques, while fundamental, present challenges such as limited scalability, subjective interpretation, and data fragmentation. Digital…
Genetic research demands precise imaging tools capable of capturing high-resolution cellular and molecular structures for in-depth analysis. 3DHISTECH’s Solutions for digital pathology supported by QuantCenter, QuantServer, SlideManager, and SlideCenter, provide an AI-driven,…
Immunology and infectious disease research require precise cellular analysis, biomarker quantification, and advanced multiplex imaging to understand immune responses, pathogen-host interactions, and disease progression. Traditional histopathology methods are labor-intensive, slow, and prone…
Molecular cell biology research relies on high-resolution imaging and fluorescence capabilities to analyze cellular structures, molecular markers, and complex biological interactions. The integration of digital pathology solutions from 3DHISTECH—Pannoramic Confocal, Pannoramic 250…
Neuroscience research demands high-resolution imaging, precise molecular analysis, and largescale data management to study the complexity of the brain, nervous system, and neurological diseases. Traditional microscopy and pathology techniques often limit the…
Toxicology research is essential for understanding the effects of drugs, chemicals, and environmental pollutants on biological systems. Traditionally, toxicology studies rely on manual histological evaluation, which can be time-consuming, prone to subjectivity,…
Toxicology and environmental science research requires high-precision imaging, high-throughput analysis, and advanced molecular assessments to evaluate the impact of toxins, chemicals, and environmental pollutants on biological systems. Traditional microscopy and histopathology methods…
Veterinary pathology plays a vital role in animal disease research, wildlife conservation, livestock farming, and food safety. As disease outbreaks, environmental changes, and food security challenges rise, digital pathology, AI-driven analysis, and…

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