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Pannoramic 480 Digital Scanner

Discover the Pannoramic 480 Digital Scanner, a high-throughput digital pathology scanner designed for large-scale laboratories and research institutions. Learn about its advanced features, including 480-slide capacity, polarization technology, and optional automated water immersion system, delivering exceptional image quality, efficiency, and reliability for demanding digital pathology workflows.

Scan Examples

Pannoramic 480 Digital Scanner

High-Throughput Digital Pathology Scanning with Polarization, Water Immersion and a 10x Objective feature

The Pannoramic 480 Digital Scanner by 3DHISTECH is a state-of-the-art digital pathology scanner designed for high-volume laboratories and research institutions. With a capacity to process up to 480 slides per batch, it redefines efficiency and scalability for demanding workflows. Built on the proven reliability of its predecessor, this next-generation scanner introduces groundbreaking features, including advanced polarization technology and an optional 40x water immersion system for unparalleled clarity and precision.

Engineered for speed and accuracy, the Pannoramic 480 delivers exceptional image quality in both single-layer and multilayer scanning, making it ideal for applications such as cytology, immunohistochemistry, and large-scale research. Its 10x objective ensures rapid processing, cutting scanning times in half compared to standard systems, while the adjustable rack priority system ensures seamless workflow optimization.

Designed to integrate effortlessly into existing laboratory setups, the Pannoramic 480 is compatible with various rack types and cover slipper machines, enhancing operational efficiency. The optional automated water immersion system elevates resolution, allowing users to visualize the intricate cellular structures with unmatched detail, particularly in high unmatched detail, particularly in high magnification applications.

Combining cutting-edge innovation with user-centric functionality, the Pannoramic 480 sets a new benchmark for digital pathology scanners. Its unparalleled capacity, precision, and flexibility make it the ultimate scanner for laboratories striving to achieve groundbreaking results with confidence and ease.

Key Features:

Exceptional Image Quality

High-resolution optics (20x – 0.8 NA, 40x – 0.95 NA) with a scientific camera ensure superior image quality and color fidelity.

Scans up to 480 slides per batch, ensuring efficient processing in high-demand research institutes without sacrificing quality.

Provides multi-layer scanning for improved depth and clearer analysis of complex cytological samples.

Ensures a seamless scanning process by isolating slides with physical issues-such as protruding coverslips or other abnormalities- into a specialized safety container. This feature prevents workflow interruptions and maintains scanning efficiency by allowing continuous processing of compliant slides while problematic ones are securely set aside for inspection and correction.

In addition to brightfield scanning, the polarization feature aids in diagnosing conditions related to birefringent materials, such as amyloid plaques in neurodegenerative diseases, or certain skin conditions that exhibit birefringence under polarized light.

Delivers ultra-clear imaging with enhanced resolution and contrast, ideal for detailed applications like cytology and immunohistochemistry.

Combines speed and precision by reducing scanning times by half as compared to other standard scanners while maintaining high-quality imaging for diverse research needs.

Features a touch interface, providing intuitive control over scanning operations and enabling immediate first level quality control inspections. This integrated Display ensures streamlined interaction with the scanner.

Engineered with an anti-vibration base, the Pannoramic 480 DX ensures maximum stability during scanning, significantly enhancing image clarity and quality. This feature minimizes external disturbances, providing consistent and precise imaging results critical for diagnostic accuracy.

The Pannoramic 480 DX is designed for seamless laboratory installation, with a modular microscope unit that can be moved and readjusted to easily fit through standard doorways, ensuring efficient installation in any lab environment.

Capacity

Up to 480 slides

Scanning

Fully Automatic Loading and Scanning

Scanning Speed

25 sec/slide*

Throughput

Up to 80 slides/hour*

Automated Objective Changer

supports up to 3 objectives

Magnification

40x / 80x, 50x / 100x, or 55x / 110x

Image Output

MRXS or DICOM format

Compatibility

Supports 3DH / Sakura Type 4768, 20-slide basket / Leica type 14051252473,30-slide basket

Illumination

Hamamatsu 20W illuminant for stable, bright imaging

Tissue Detection

Fully Automated, AI-Based

Slide Size

Supports both single- and double-width slides**

Focus Layering

Single, multi-, and extended focus-layer scanning

Barcode Reading

1D and 2D barcode capability

Dimensions

1195 mm x 902 mm x 1004 mm

Weight

240 kg

Pannoramic 480 Digital Scanner

Specifications

Customizable Configurations

Objective Preferences:

  • 20x NA 0.8
  • 10x NA 0.45
  • 20x NA 0.8 and 40x 0.95
  • w40x/1.2 NA (Optional and requires an immersion system installed)

Image Digitalization:

  • 25 MP CIS CMOS digital imaging camera (DEFAULT)
  • 12 MP Adimec CMOS digital imaging camera

Customizable Configurations: (choose between Automated slide loading for either single- or double-width slides**)

  • Automated slide loading for single-width slides (DEFAULT)
  • Automated slide loading for double-width slides

Optional Automated Water Immersion System:

  • 40x water immersion objective with automated immersion system

Key features of the automated immersion system:

    • Significantly increases numerical aperture, allowing for improved light capture and detail, particularly in high magnification imaging
    • Exceptional optical performance for visualizing cellular and subcellular structures
    • Ensures consistent application of the immersion medium, optimizing scan quality and minimizing manual intervention

 

Notes

*Based on 40x magnification, 0.24 µm/pixel resolution, single-layer scanning

Use Cases of Pannoramic 480 Digital Scanner

Explore the Use Cases

Archaeology and paleontology have traditionally relied on destructive sampling methods such as sectioning, staining, and thin-section petrography to study fossils and artifacts at the microscopic level. However, these approaches pose risks to…
Cancer research demands cutting-edge imaging technologies to enhance biomarker discovery, tumor profiling, and immuno-oncology advancements. Traditional histopathology techniques, while fundamental, present challenges such as limited scalability, subjective interpretation, and data fragmentation. Digital…
Geological and mineralogical research relies on high-resolution imaging techniques to analyze mineral composition, rock microstructures, and sedimentary formations. Traditional petrographic microscopy, while effective, is often limited by sample preparation constraints, depth resolution,…
Neuroscience research demands high-resolution imaging, precise molecular analysis, and largescale data management to study the complexity of the brain, nervous system, and neurological diseases. Traditional microscopy and pathology techniques often limit the…
Pharmacology research is essential for drug discovery, preclinical evaluation, and biomarker validation. However, researchers face significant challenges in high-throughput tissue analysis, biomarker quantification, and data integration. Traditional microscopy and manual pathology workflows…
Toxicology research is essential for understanding the effects of drugs, chemicals, and environmental pollutants on biological systems. Traditionally, toxicology studies rely on manual histological evaluation, which can be time-consuming, prone to subjectivity,…
Toxicology and environmental science research requires high-precision imaging, high-throughput analysis, and advanced molecular assessments to evaluate the impact of toxins, chemicals, and environmental pollutants on biological systems. Traditional microscopy and histopathology methods…

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