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Pannoramic 250 FLASH III Digital Scanner

Developed for research innovation, this 300-slide scanner delivers rapid brightfield imaging, advanced fluorescence capabilities with 45 channels, AI-driven tissue detection, and Z-stack options, transforming demanding workflows with meticulous attention to detail.
Pannoramic 250 FLASH III

Scan Examples

Pannoramic 250 FLASH III Digital Scanner

Advancing Whole Slide Imaging for Research

The Pannoramic 250 Flash III sets a new standard in research- focused whole slide imaging. Designed for laboratories seeking unparalleled performance, this high-speed digital slide scanner offers a 300-slide capacity and supports both brightfield and fluorescence scanning with up to 45 logical fluorescent channels. Its state-of-the-art imaging optics achieve an exceptional resolution of 0.12 um/pixel, ensuring every detail is captured with precision.

Featuring next-generation automation, including AI-powered tissue detection and Z-stack scanning, the Pannoramic 250 Flash III transforms complex workflows into simplified processes. Its continuous loading system keeps up with demanding workloads, while its intelligent software unlocks new levels of precision and productivity. Designed for forward-thinking laboratories, this scanner blends innovation, versatility, and technological sophistication, setting it apart as a true pioneer in whole-slide imaging for research excellence.

Key Features:

Unmatched Brightfield and Fluorescence Scanning

Achieve precise imaging with 0.12 um/pixel resolution and advanced fluorescence capabilities, supporting up to 45 logical channels for comprehensive research applications.

Process up to 300 slides with continuous loading and automated tissue detection, ensuring efficiency for demanding workloads.

Powered by high-resolution Plan Apochromat objectives and cutting-edge CMOS imaging, capturing every detail with unparalleled clarity.

Features AI-driven tissue detection, auto-focus scanning, and optional Z-stack imaging to simplify complex workflows.

Equipped with high-end illumination engines, 9 filter positions, and multiband filter support, offering superior flexibility for fluorescence applications.

Includes SlideCenter, SlideManager, QuantCenter and other software and modules for intuitive slide management, barcode integration, and seamless data handling.

Capacity

Up to 300 slides (12 magazines of 25 slides each)

Scanning

Brightfield and fluorescence whole-slide scanning with automated tissue detection and coverslip detection. Fully Automated Scanning Process

Brightfield Scanning Speed

36 seconds per slide

Fluorescence Scanning Speed

8 minutes 30 seconds per slide (15mm x 15mm, 0.33um/pixel, 3 fluorescent channels)

Throughput

Brightfield – Up to 60 slides/hour at 0.24 um/pixel resolution

Objectives

20x/0.8 NA and 40x/0.95 NA

Number of Supported Objectives

Up to 2 (Dual) Optional fluorescence specific objectives available.

Brightfield Magnification

40x / 80x

Fluorescence Magnification

30x/60x, or up to 115x depending on configuration

Image Output

MRXS, JPG, JPEGXR, BMP, PNG formats for export; compatible with DICOM and other standard formats for import/export

Compatibility

Single standard slides (75mm x 25mm) with coverslip thickness of No. 1 or 1.5 (0.13 to 0.19mm)

Flash Scanning

Yes

Brightfield Scanning (resolution)

0.12 um/pixel resolution using advanced optical and camera systems

Fluorescence scanning (resolution)

45 logical channels, 9 physical filter positions, multiband filter support, and high-end fluorescence illumination engines.

Brightfield Illumination

Precision-Aligned Pulse Xenon Light Source

Fluorescence Illumination

Lumencor SOLA U-nir, SPECTRA III or COOL LED

Tissue Detection

AI-Based, fully automated

Slide Size

Compatible with single-width slides; supports 75mm x 25mm with 0.9 to 1.2mm thickness

Focus Layering

Single, multi-, and extended focus-layer scanning

Barcode Reading

1D and 2D barcode capability for slide identification, including Code39, QR, Data Matrix and more

Dimensions

680 mm x 690 mm x 550 mm

Weight

46 kg (49kg with fluorescence option)

Pannoramic 250 FLASH III Digital Scanner

Specifications

Customizable Configurations

Available Objectives:

  • 20x/0.8 NA (Default)
  • 20x/0.8 NA and 40x/0.95 NA
  • 10x/0.3 Plan-Apochromat objective (optional for lower magnification needs, available for fluorescence only)

Image Digitalization:

  • 12 MP CMOS camera (Default)
  • 25 MP CIS CMOS digital imaging camera (Optional)
  • 4.2 MP sCMOS camera (Optional, specifically for fluorescence applications)
  • 5 MP (Optional, fluorescence specific)

Additional Options:

  • Motorized Objective Changer (Included when two objectives are selected, as the standard configuration includes a single objective.)
  • Multilayer (Z-Stack) Scanning
  • Extended Focus Scanning

Use Cases of Pannoramic 250 FLASH III Digital Scanner

Explore the Use Cases

Genetic research demands precise imaging tools capable of capturing high-resolution cellular and molecular structures for in-depth analysis. 3DHISTECH’s Solutions for digital pathology supported by QuantCenter, QuantServer, SlideManager, and SlideCenter, provide an AI-driven,…
Immunology and infectious disease research require precise cellular analysis, biomarker quantification, and advanced multiplex imaging to understand immune responses, pathogen-host interactions, and disease progression. Traditional histopathology methods are labor-intensive, slow, and prone…
Molecular cell biology research relies on high-resolution imaging and fluorescence capabilities to analyze cellular structures, molecular markers, and complex biological interactions. The integration of digital pathology solutions from 3DHISTECH—Pannoramic Confocal, Pannoramic 250…
Toxicology and environmental science research requires high-precision imaging, high-throughput analysis, and advanced molecular assessments to evaluate the impact of toxins, chemicals, and environmental pollutants on biological systems. Traditional microscopy and histopathology methods…
Veterinary pathology plays a vital role in animal disease research, wildlife conservation, livestock farming, and food safety. As disease outbreaks, environmental changes, and food security challenges rise, digital pathology, AI-driven analysis, and…

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