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Pannoramic 150 Digital Scanner

The Pannoramic 150 is a versatile digital pathology system designed for high-speed, high-resolution brightfield and fluorescence scanning. Equipped with a continuously moving stage, advanced Plan-Apochromat optics including a 10x objective, and a back-illuminated sCMOS camera, it delivers exceptional image clarity and efficiency for research applications.

Scan Examples

Pannoramic 150 Digital Scanner

Pannoramic 150 – High Throughput Digital Slide Scanner for Advanced Brightfield and Fluorescence Imaging

The Pannoramic 150 sets a new standard in digital pathology and whole-slide imaging with high-speed, high-resolution scanning for both brightfield and fluorescence applications. Designed for high-throughput research, it combines cutting-edge optics, automation, and software integration to deliver unparalleled performance, accuracy, and efficiency. With a 150-slide capacity and continuous loading, it eliminates workflow bottlenecks, enabling labs to process more slides in less time. Its Plan-Apochromat 40x/0.95 NA objective achieves 103x magnification at 0.10 µm/pixel resolution, producing publication-quality brightfield images with exceptional clarity. The continuously moving stage and 72 fps brightfield color camera further enhance speed without sacrificing detail.

A key differentiator is its exclusive 10x fluorescence objective, an innovation unique to 3DHISTECH that reduces fluorescence scan time by 50% compared to conventional scanners. Unlike competitor systems that rely solely on higher magnifications, the Pannoramic 150 combines high-speed fluorescence imaging with uncompromised resolution and sensitivity. This groundbreaking feature, paired with a back-illuminated 16-bit 4.2 MP sCMOS camera, 9-position motorized fluorescence filter changer, and high-end multiband light engine, provides unmatched speed and efficiency for multiplexed fluorescence imaging. Automated slide handling, barcode reading, and tissue detection further streamline the workflow, reducing manual workload and increasing productivity.

With faster, more reliable results, the Pannoramic 150 allows researchers to focus on data interpretation instead of troubleshooting technical issues. Less hands-on time means more productivity, as automated slide loading, barcode detection, and intelligent focus adjustment free up valuable research hours. The high-resolution brightfield and fluorescence imaging enhance data accuracy, delivering clearer, more detailed results for confident decision-making. Scalable for any lab size, it seamlessly adapts to both small-scale studies and high-volume research projects, ensuring efficiency without compromise. With its cutting-edge technology, automation-driven workflow, and superior imaging capabilities, the Pannoramic 150 is more than just a scanner, it’s an essential tool that simplifies your work, boosts efficiency, and improves research outcomes.

Key Features:

High-Throughput Scanning with 150-Slide Capacity – More Work Done in Less Time

Eliminates workflow bottlenecks and maximizes lab efficiency, enabling researchers to process more samples faster.

  • The 150-slide capacity (6 magazines of 25 slides) with continuous loading allows you to scan large batches without manual intervention.
  • Fully automated slide handling, barcode reading, and tissue detection reduce hands-on time, allowing you to focus on analysis rather than slide management.

Produces publication-quality images for precise morphological assessment, reducing the need for rescanning.

  • The continuously moving stage ensures smooth and high-speed scanning without compromising quality.
  • A dedicated 5 MP color CMOS camera (72 fps frame rate) captures sharp, vibrant images with high color fidelity.
  • Plan-Apochromat 40x/0.95 NA objective achieves 103x magnification at 0.10 µm/pixel resolution, making even the smallest histological details visible.

Speeds up fluorescence-based research, allowing for faster data collection, reducing sample exposure, and improving experiment efficiency.

  • Equipped with a 10x fluorescence objective, cutting fluorescence scan time in half compared to conventional scanners.
  • Back-illuminated 16-bit 4.2 MP sCMOS camera ensures optimal sensitivity, even for low-intensity signals.
  • 9-position motorized fluorescence filter changer with multiband filter support enables highly flexible and multiplexed imaging.

Minimizes manual adjustments, leading to more consistent and reliable results while reducing user fatigue.

  • Fast multicolor fluorescence pre-scan for precise sample detection.
  • Software-driven flat-field correction and deconvolution ensure uniform illumination and enhanced signal-to-noise ratio.
  • Automated tissue and coverslip detection improves scanning accuracy.

Simplifies data management, collaboration, and remote analysis, saving time and making research workflows smoother.

  • Fully automated operation with server-side barcode reading for efficient slide tracking and data integrity.
  • Integration with Pannoramic Scanner Software, SlideViewer, SlideManager, and Quant for streamlined data analysis.
  • Multiple scanning profiles and adjustable focus parameters adapt to a variety of research needs.
Capacity

150 slides (6 magazines, 25 slides each) with automatic loading and continuous scanning

Scanning

Dual-mode scanning (brightfield and fluorescence) with area scanning and autofocus

Motorized Camera Changer

Included, for seamless transitions between BF and FL imaging modes without manual intervention

Motorized Objective changer

Included when two objectives are selected (supports two objectives)

Brightfield Scanning Speed

1 minute 30 seconds for a 15 mm x 15 mm area at 0.19 µm/pixel resolution

Fluorescence Scanning Speed

8 minutes 30 seconds for a 15 mm x 15 mm area with 3 fluorescent channels at 20 ms exposure time

Throughput

Optimized for high-throughput workflows with fully automated slide handling

Objectives

Plan-Apochromat 10x/0.3 NA, 20x/0.8 NA, and 40x Corr/0.95 NA objectives

Brightfield Magnification

Up to 103x

Fluorescence Magnification

Up to 98x (with 1.6x adapter)

Image Output

MRXS format with export options to JPG, JPEGXR, BMP, PNG, TIFF, Roche TIFF, SVS, and DICOM

Slide Compatibility

Slides measuring 75.0-76.2 mm (L) x 25.0-26.0 mm (W) x 0.9-1.2 mm (T) with No. 1 or 1.5 coverslips (0.13-0.19 mm)

Flash scanning

Not explicitly specified

Brightfield Scanning (resolution)

Down to 0.10 µm/pixel (with 40x objective)

Fluorescence scanning (resolution)

Down to 0.10 µm/pixel (with 40x objective and 1.6x adapter)

Brightfield Illumination

LED-based transmitted light with 3DHISTECH LED FLASH technology (average lifetime ~60,000 hours)

Fluorescence Illumination

Lumencor SOLA, Spectra III, or CoolLED pE-800 Light Engine with 8 solid-state sources (LEDs and lasers, 380-740 nm)

Tissue Detection

Automatic threshold tissue detection with a USB preview camera

Slide Size

75.0-76.2 mm (L) x 25.0-26.0 mm (W) x 0.9-1.2 mm (T)

Focus Layering

Optional Z-stack (multilayer) scanning with 1-30 layers and adjustable distances (0.2-2 µm)

Barcode Reading

Supports 1D and 2D barcode types, including Code39, Code128, QR, and Data Matrix

Dimensions

Approx. 673 mm x 689 mm x 546 mm (scanner unit)

Weight

Approx. 49 kg (scanner unit)

Pannoramic 150 Digital Scanner

Specifications

Customizable Configurations

Available Objectives:

  • 20x/0.8 NA (Default)
  • 20x/0.8 NA and 40x/0.95 NA
  • 10x/0.3 Plan-Apochromat objective (optional, available for fluorescence only)

Additional Options:

  • Motorized Objective Changer (Included when two objectives are selected, as the standard configuration includes a single objective.)
  • Multilayer (Z-Stack) Scanning
  • Extended Focus Scanning

Use Cases of Pannoramic 150 Digital Scanner

Explore the Use Cases

Botany and plant sciences rely on high-resolution imaging and precise analysis of plant tissues to understand disease mechanisms, stress responses, genetic modifications, and ecological changes. Traditional microscopy techniques limit research efficiency due…
Cancer research demands cutting-edge imaging technologies to enhance biomarker discovery, tumor profiling, and immuno-oncology advancements. Traditional histopathology techniques, while fundamental, present challenges such as limited scalability, subjective interpretation, and data fragmentation. Digital…
Genetic research demands precise imaging tools capable of capturing high-resolution cellular and molecular structures for in-depth analysis. 3DHISTECH’s Solutions for digital pathology supported by QuantCenter, QuantServer, SlideManager, and SlideCenter, provide an AI-driven,…
Molecular cell biology research relies on high-resolution imaging and fluorescence capabilities to analyze cellular structures, molecular markers, and complex biological interactions. The integration of digital pathology solutions from 3DHISTECH—Pannoramic Confocal, Pannoramic 250…
Neuroscience research demands high-resolution imaging, precise molecular analysis, and largescale data management to study the complexity of the brain, nervous system, and neurological diseases. Traditional microscopy and pathology techniques often limit the…
Toxicology research is essential for understanding the effects of drugs, chemicals, and environmental pollutants on biological systems. Traditionally, toxicology studies rely on manual histological evaluation, which can be time-consuming, prone to subjectivity,…
Veterinary pathology plays a vital role in animal disease research, wildlife conservation, livestock farming, and food safety. As disease outbreaks, environmental changes, and food security challenges rise, digital pathology, AI-driven analysis, and…

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