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TMA Grand Master

The TMA Grand Master automates tissue microarray creation with exceptional speed, precision, and reliability. Designed for high-throughput institutions, it ensures accurate core selection and placement, reducing manual effort while increasing reproducibility. With advanced features and intuitive operation, it outperforms traditional methods and competing systems in efficiency and consistency, making it the ultimate tool for institutional pathology labs, biobanks, large research centers, and pharmaceutical companies.
tma grand master
TMA Grand Master

TMA Grand Master – The Ultimate High-Throughput TMA

The TMA Grand Master is the industry-leading automated tissue microarrayer in the market, designed to streamline high-throughput tissue microarray (TMA) creation with unmatched precision, speed, and reliability. Engineered for research, biomarker studies, and drug development, it automates the selection, coring, and placement of tissue samples, significantly reducing manual workload while ensuring exceptional reproducibility. With its high-capacity design, the TMA Grand Master can process up to 72 recipient blocks and 600 donor blocks in a single run, far surpassing traditional methods and competing systems.

Its intelligent software allows for precise core selection, automated tissue recognition, and real-time visualization, minimizing human error and maximizing efficiency. The system’s high-speed robotic arm ensures accurate and consistent placement, while its barcode-based tracking enhances sample traceability. Designed for laboratories that demand both scalability and reliability, the TMA Grand Master sets the standard in automated TMA production – Featuring fully automated walkaway operation, 72 blocks capacity, 4 core diameters, ability to create clone blocks (identical TMAs), sample extraction feature for molecular analysis in PCR tubes (6 PCR casette, 10 PCR tube in each).

Key Features:

Market-Leading Speed and Capacity
  • Fastest fully automated tissue microarrayer available
  • Processes 72 blocks simultaneously (60 donor, 12 recipient)
  • High-speed operation – Processes up to 280 cores per hour
  • Four core diameters: 0.6mm, 1mm, 1.5mm, and 2 mm
  • High-density arraying: Up to 558 cores per block (0.6mm cores)
  • Custom recipient block design for tailored applications
  • Digital slide overlay for precise tissue core selection
  • Automatic block height measurement for perfect alignment
  • Integrated barcode scanning (1D and 2D) for efficient tracking
  • Automatic donor block and label image saving for documentation
  • Project data automatically saved to database for seamless analysis
  • PCR extraction function for downstream molecular pathology applications
  • Accommodates 6 PCR cassettes (each holding 10 PCR tubes)
  • FFPE tissue samples ready for DNA extraction and PCR analysis
  • Cleaning block integration to prevent cross-contamination
  • Imports clinical data and integrates with research workflows
  • Exports TMA data in multiple formats (ODS, XLS, XLSX, CSV, XML)
  • Compatible with digital pathology workflows, including MRXS and JPEG image formats
  • TMA Control software enables intuitive block design and tissue selection
  • Automated digital slide alignment ensures precise core placement
  • Comprehensive project tracking and TMA data management for streamlined analysis

 

Software & Workflow Integration
  • Total block capacity: 72 blocks (60 donor, 12 recipient)
  • Maximum core throughput: 250-280 cores per hour
  • Maximum cores per TMA block:
  • 6 mm cores: 558
  • mm cores: 286
  • 5 mm cores: 135
  • 0 mm cores: 84
Precision & Core Selection
  • Core diameter options: 0.6 mm, 1 mm, 1.5 mm, 2 mm
  • Automated donor block image recording for precise tissue selection
  • Digital slide integration: Supports MRXS and JPEG formats for sample designation
  • Fully automated barcode scanning: 1D and 2D
Automation & Data Management
  • Parallel processing: Simultaneous block loading, imaging, drilling, and punching
  • Automated block height measurement ensures perfect core alignment
  • Project data automatically saved to the internal database
  • TMA data export formats: ODS, XLS, XLSX, CSV, XML
Molecular Pathology Support
  • PCR extraction function:
  • 6 PCR cassettes, each holding 10 PCR tubes
  • Extracted FFPE tissue samples ready for DNA extraction and PCR analysis
  • Cleaning block integration to prevent cross-contamination
Physical Specifications
  • Dimensions (W x D x H): 80 x 50 x 46 cm
  • Weight: 48 kg

 

Software & Workflow Integration
  • Control Software: TMA Grand Master is powered by the latest TMA Control software, designed for precise block layout, core selection, and digital slide overlay.
  • Seamless workflow management: Automatically saves all TMA data for streamlined analysis with TMA Module software.
TMA Grand Master

Specifications

Use Cases of TMA Grand Master

Explore the Use Cases

Genetic research demands precise imaging tools capable of capturing high-resolution cellular and molecular structures for in-depth analysis. 3DHISTECH’s Solutions for digital pathology supported by QuantCenter, QuantServer, SlideManager, and SlideCenter, provide an AI-driven,…
Immunology and infectious disease research require precise cellular analysis, biomarker quantification, and advanced multiplex imaging to understand immune responses, pathogen-host interactions, and disease progression. Traditional histopathology methods are labor-intensive, slow, and prone…
Neuroscience research demands high-resolution imaging, precise molecular analysis, and largescale data management to study the complexity of the brain, nervous system, and neurological diseases. Traditional microscopy and pathology techniques often limit the…
Toxicology research is essential for understanding the effects of drugs, chemicals, and environmental pollutants on biological systems. Traditionally, toxicology studies rely on manual histological evaluation, which can be time-consuming, prone to subjectivity,…

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