The Pannoramic-X is set to transform the research landscape with its state-of-the-art, DVREAL 3D Imaging. As a cutting-edge CAT scanner optimized for medium to high-resolution three-dimensional scans, it leverages soft x-rays to deliver superior sensitivity to chemical compositions. This revolutionary instrument is designed to enhance tissue visualization with DVREAL (Digitally scanned, Virtually sectioned and stained) 3D Imaging, enable quantitative biomarker analysis, and facilitate virtual collaboration, significantly advancing cancer research and integrating seamlessly with molecular pathology techniques. These research advancements are crucial for more accurate diagnoses, personalized treatment strategies, and improved patient outcomes in cancer care.
DVREAL 3D IMAGING
Pannoramic-X: Advanced 3D Imaging
The Pannoramic-X sets a new standard in 3D pathology imaging by capturing and analyzing whole formalin-fixed, paraffin-embedded (FFPE) tissue blocks and megablocks in unprecedented detail. This comprehensive suite of features ensures exceptional resolution for low-contrast samples and accommodates large tissue samples, providing unparalleled flexibility in research applications. Innovative digital processes, such as virtual slicing and staining, replicate traditional histological techniques, preserving the integrity of samples without sectioning.
Improving Patient Outcomes
The Pannoramic-X’s ability to perform comprehensive assessments of tumor morphology and clinically relevant features supports precise research and personalized treatment strategies. Detecting vascular invasion is crucial for determining cancer stages and guiding treatment decisions, while identifying LVI and tumor budding is essential for prognosis and understanding disease progression. These capabilities collectively contribute to improved patient outcomes by enabling more accurate diagnoses and tailored treatment plans.
A Huge Leap Forward
The Pannoramic-X represents a significant leap forward in cancer pathology, offering unparalleled capabilities in 3D imaging. Its advanced features and applications not only enhance research, but also pave the way for breakthroughs in personalized medicine and other scientific fields. With the Pannoramic-X, the future of pathology and beyond is more detailed, accurate, and impactful than ever before.
Key Features and Applications
Pannoramic-X Software
Tumor Analysis and Diagnostic Imaging
- Provides detailed insights into tumor morphology and distribution.
- Offers high-resolution scans for accurate detection of clinically relevant features, such as lymphovascular invasion (LVI) and tumor budding.
- Enhances surgical precision with rapid, high-resolution imaging.
- Comprehensive Tumor Characterization: Micro CT provides detailed and accurate characterization of tumor deposits.
Supporting Research in In Vivo Diagnostics
- Utilizes MicroCT for histopathological assessment of tissue resected via endoscopic submucosal dissection (ESD).
- Assesses the feasibility of MicroCT in detecting pathological alterations in paraffin blocks of rectal cancer specimens.
Margin Detection and Surgical Guidance
- CT scans offer comprehensive guidance during margin detection surgery, aiding in the accurate determination of melanoma lesion depth.
Innovative Imaging and Analysis Features
- Whole FFPE Imaging: PANNORAMIC-X captures and analyzes entire tissue blocks and megablocks without sectioning, preserving sample integrity.
- Virtual Slicing and Staining: Digital processes replicate traditional histological techniques.
- Versatile Slicing: Allows slicing in any plane.
- High Detail Scanning: Delivers exceptional resolution for low-contrast samples, ensuring no detail is missed.
- Megablock Imaging: Accommodates large tissue samples, providing flexibility in research applications, especially for large volumes.
- Ergonomic and Intuitive Software: CT Control and 3DView software enable 3D reconstructions, precise volumetric analysis, and advanced visualization.
High-Resolution Scans for Geology Research and Other Disciplines
- Applies to various fields including geology, biology, and material sciences.
- Contributes significantly to oil and gas exploration by identifying critical data within scanned drill samples.
CT Control Software
The CT Control Software enables researchers to diagnose digital x-ray images in both three-dimensional and two-dimensional views, request further examinations, and conduct histological analyses. The software allows for easy determination of the ideal cutting plane based on CT images, ensuring fast, cost-effective, and reproducible quantitative test results.
Key features include:
- Digital archiving of specimens.
- Quality assurance of FFPE blocks.
- Precise volumetric analysis of specimens (e.g., tumor volume).
- Pre-screening of specimens prior to costly staining procedures.
- 3D visualization of cell-tissue interactions.
- Post-operative macroscopic scanning of whole organs.
- Variable sample sizes from millimeters to decimeters depending on configuration.
3DView
The 3DView Software prepares 3D reconstructions from 2D serial sections and 2D sections with Z layers.
Key features include:
- Slice and volume views of volumetric datasets.
- Color manipulation and adjustments to viewing parameters.
- Measurement tools for assessing metric distances and segmentation analysis.
- Advanced visualization options allowing users to select and edit numerous staining for optimal visualization (2D and 3D) with file export options.
Advanced Image Analysis Software Solutions
The Pannoramic-X includes sophisticated image analysis capabilities, such as PatternQuant and NuclearQuant offering high-speed, cell-based measurements and customizable workflows. These tools ensure precise, reproducible results tailored to the specific needs of each research project.
Features include:
- New, easy-to-use workflow management
- Support for multi-level measurements
- Hierarchical annotation
- Pattern recognition-based pre-segmentation
- Process management
- Fast image processing
PatternQuant – A new trainable pattern recognition application
NuclearQuant – High-speed, cell-based, whole slide measurement
Why Choose the Pannoramic-X?
- No Depth or Size Limitations: Capable of scanning any organ or tissue type in FFPE blocks of any size.
- No Sectioning Required: Ideal for organs challenging traditional pathology.
- High-Volume Scanning: Capable of scanning large volumes.
- Closet Cabinet System: Radiation safe with zero emissions.
- No Special Facility Requirements: Fits into any lab environment.
- Cost-Effective: Operates on standard domestic electricity, making it accessible and affordable.
- User-Friendly Interface: Familiar visualization experience.
- Simple Operation: No need for an engineer; a technical person is sufficient.
- Compatibility: Integrates with HIS and LIS systems.
- Expanded Research Horizons: Opens new possibilities for research.
Specifications
| Sample Format | Few mm to 150mm |
| X-ray Source | Micro-focus, 70kV, 7W source. (250W option in 2025) |
| Scanning Time | Typically 20 minutes to a few hours for very high quality images |
| Operational Use | 24/7 operation |
| Samples | Multiple samples can be loaded at once, sample changer is optional |
| Format | MRXS, PACS in DICOM, Raw (fully documented format) |
| Dimensions (WxDxH) | 1790W x 929D x 1820H (without the monitor console) |
| Weight | 1150kg over 2000x2800mm, below 500kg/m2 |
Important Notice
The PANNORAMIC-X, micro CT is for research use only, and cannot be used for patient diagnosis.
Product Brochures:
Pannoramic-X Research Solutions
