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Pannoramic 75 Digital Scanner

The Pannoramic 75 is a versatile digital slide scanner designed for high-resolution brightfield and fluorescence whole-slide imaging. With a 75-slide capacity, automated scanning Equipped with a continuously moving stage, advanced Plan-Apochromat optics including a 10x objective, and a back-illuminated sCMOS camera, it delivers exceptional image clarity and efficiency for research applications.

Scan Examples

Pannoramic 75 Digital Scanner

Pannoramic 75 – 75 capacity Digital Slide Scanner for Advanced Brightfield and Fluorescence Imaging

The Pannoramic 75 is a high-performance digital slide scanner designed for brightfield and fluorescence whole-slide imaging. With a 75-slide capacity, fully automated scanning, and advanced imaging capabilities, it provides exceptional speed, accuracy, and efficiency for research laboratories and digital pathology applications. Equipped with a continuously moving stage, a 72 fps brightfield color camera, and a back-illuminated 16-bit 4.2 MP sCMOS fluorescence camera, the system delivers superior image quality with minimal noise.

A key advantage of the Pannoramic 75 is its 10x fluorescence objective, which is exclusive to 3DHISTECH and cuts fluorescence scanning time in half compared to conventional fluorescence scanners. This innovation allows researchers to achieve faster, high-resolution fluorescence imaging without compromising sensitivity. The system also features a 9-position motorized fluorescence filter changer, a high-end multiband light engine, and automated tissue and barcode detection, making it a versatile tool for multiplexed fluorescence imaging.

 The Pannoramic 75 enhances workflow efficiency by reducing hands-on time and automating key imaging processes. With server-side barcode reading, multiple scanning profiles, and fully automated slide handling, users can focus more on research and analysis rather than manual adjustments. The high-resolution imaging capabilities ensure clearer, more detailed results, allowing for confident decision-making in complex research applications. Whether handling low-volume or high-throughput workflows, the Pannoramic 75 adapts seamlessly, making it an indispensable solution for modern laboratories.

Key Features:

High-Throughput Scanning with 75-Slide Capacity – More Work Done in Less Time

Eliminates workflow bottlenecks and maximizes lab efficiency, enabling researchers to process more samples faster.

  • The 75-slide capacity (3 magazines of 25 slides each) with continuous loading allows you to scan large batches without manual intervention.
  • Fully automated slide handling, barcode reading, and tissue detection reduce hands-on time, allowing you to focus on analysis rather than slide management.
  • Motorized objective changer for easy switching between 10x, 20x and/or 40x objectives (included when two objectives are selected)

 

Produces publication-quality images for precise morphological assessment, reducing the need for rescanning.

  • The continuously moving stage ensures smooth and high-speed scanning without compromising quality.
  • A dedicated 5 MP color CMOS camera (72 fps frame rate) captures sharp, vibrant images with high color fidelity.
  • Plan-Apochromat 40x/0.95 NA objective achieves 103x magnification at 0.10 µm/pixel resolution, making even the smallest histological details visible.

Speeds up fluorescence-based research, allowing for faster data collection, reducing sample exposure, and improving experiment efficiency.

  • Equipped with a 10x fluorescence objective, cutting fluorescence scan time in half compared to conventional scanners.
  • Back-illuminated 16-bit 4.2 MP sCMOS camera ensures optimal sensitivity, even for low-intensity signals.
  • 9-position motorized fluorescence filter changer with multiband filter support enables highly flexible and multiplexed imaging.

 

Minimizes manual adjustments, leading to more consistent and reliable results while reducing user fatigue.

  • Fast multicolor fluorescence pre-scan for precise sample detection.
  • Software-driven flat-field correction and deconvolution ensure uniform illumination and enhanced signal-to-noise ratio.
  • Automated tissue and coverslip detection improves scanning accuracy.

Simplifies data management, collaboration, and remote analysis, saving time and making research workflows smoother.

  • Fully automated operation with server-side barcode reading for efficient slide tracking and data integrity.
  • Integration with Pannoramic Scanner Software, SlideViewer, SlideManager, and Quant for streamlined data analysis.
  • Multiple scanning profiles and adjustable focus parameters adapt to a variety of research needs.

 

Capacity

75 slides (3 magazines, 25 slides each) with automatic loading and continuous scanning.

Scanning

Dual-mode scanning (brightfield and fluorescence) with area scanning and autofocus.

Motorized Camera Changer

Included, for seamless transitions between BF and FL imaging modes without manual intervention

Motorized Objective changer

Included when two objectives are selected (supports two objectives)

Brightfield Scanning Speed

1 minute 30 seconds for a 15 mm x 15 mm area at 0.19 µm/pixel resolution.

Fluorescence Scanning Speed

8 minutes 30 seconds for a 15 mm x 15 mm area with 3 fluorescent channels at 20 ms exposure time.

Throughput

Optimized for high-throughput workflows with fully automated slide handling.

Objectives

Plan-Apochromat 10x/0.3 NA, 20x/0.8 NA, and 40x Corr/0.95 NA objectives.

Brightfield Magnification

Up to 103x

Fluorescence Magnification

Up to 98x (with 1.6x adapter)

Image Output

MRXS format with export options to JPG, JPEGXR, BMP, PNG, TIFF, Roche TIFF, SVS, and DICOM

Slide Compatibility

Slides measuring 75.0-76.2 mm (L) x 25.0-26.0 mm (W) x 0.9-1.2 mm (T) with No. 1 or 1.5 coverslips (0.13-0.19 mm)

Flash scanning

Not explicitly specified

Brightfield Scanning (resolution)

Down to 0.10 µm/pixel (with 40x objective)

Fluorescence scanning (resolution)

Down to 0.10 µm/pixel (with 40x objective and 1.6x adapter)

Brightfield Illumination

LED-based transmitted light with 3DHISTECH LED FLASH technology (average lifetime ~60,000 hours)

Fluorescence Illumination

Lumencor SOLA, Spectra III, or CoolLED pE-800 Light Engine with 8 solid-state sources (LEDs and lasers, 380-740 nm)

Tissue Detection

Automatic threshold tissue detection with a USB preview camera

Slide Size

75.0–76.2 mm (L) x 25.0–26.0 mm (W) x 0.9–1.2 mm (T)

Focus Layering

Optional Z-stack (multilayer) scanning with 1–30 layers and adjustable distances (0.2–2 µm)

Barcode Reading

Supports 1D and 2D barcode types, including Code39, Code128, QR, and Data Matrix

Dimensions

Approx. 673 mm x 689 mm x 546 mm (scanner unit)

Weight

Approx. 49 kg (scanner unit)

Pannoramic 75 Digital Scanner

Specifications

Customizable Configurations

Available Objectives:

  • 20x/0.8 NA (Default)
  • 40x/0.95 NA
  • 10x/0.3 Plan-Apochromat objective (optional, available for fluorescence only)

 

Additional Options:

  • Motorized Objective Changer (Included when two objectives are selected, as the standard configuration includes a single objective.)
  • Multilayer (Z-Stack) Scanning
  • Extended Focus Scanning

Use Cases of Pannoramic 75 Digital Scanner

Explore the Use Cases

Genetic research demands precise imaging tools capable of capturing high-resolution cellular and molecular structures for in-depth analysis. 3DHISTECH’s Solutions for digital pathology supported by QuantCenter, QuantServer, SlideManager, and SlideCenter, provide an AI-driven,…

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